Monitor the patients lung and cardiovascular status closely. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. All dry powder inhaler products: If you have a milk allergy. The manufacturer recommends avoiding concurrent use of tetrabenazine with other drugs known to prolong QTc, such as beta-agonists. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. Donepezil; Memantine: (Minor) Use donepezil with caution in combination with short-acting beta-agonists as concurrent use may increase the risk of QT prolongation. Coadministration may increase the risk for QT prolongation and torsade de pointes (TdP). Histrelin: (Minor) Consider whether the benefits of androgen deprivation therapy (i.e., histrelin) outweigh the potential risks of QT prolongation in patients receiving short-acting beta-agonists. Albuterol is used by some veterinarians as a tocolytic agent to suppress uterine contractions when prema… Aspirin, ASA; Caffeine; Orphenadrine: (Moderate) Sensitive patients may wish to limit or avoid excessive caffeine intake from foods, beverages, dietary supplements and medications during therapy with beta-agonists. Safety and efficacy have not been established; nebulizer inhalation maximum dependent on patient response and formulation used. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses and/or when associated with hypokalemia. Setting: Large urban emergency department (ED). This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Higher maximum dosages for inhalation products have been recommended in NAEPP guidelines for acute exacerbations of asthma. As previously mentioned, Albuterol doses should be slowly ramped upwards until the peak dose is achieved, and the peak optimal dose might be different for different individuals (some individuals might be more sensitive to stimulants than others). The Global Initiative for Asthma (GINA) guidelines recommend 2.5 mg via nebulization with mouthpiece (and facemask in those younger than 4 years) every 20 minutes for the first hour for acute exacerbations, with reassessment thereafter (further dosing not specified). Gemifloxacin may prolong the QT interval in some patients. (Minor) Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses and/or when associated with hypokalemia. The action of beta-agonists on the cardiovascular system may be potentiated by a halogenated anesthetic. Loratadine; Pseudoephedrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Halothane: (Minor) Halothane, like other halogenated anesthetics, can prolong the QT interval. Beta-agonists should be administered with caution to patients being treated with drugs known to prolong the QT interval because the action of beta-agonists on the cardiovascular system may be potentiated. Max: 32 mg/day PO. Max: 32 mg/day PO. Close observation for such effects is prudent, particularly if beta-agonists are administered within two weeks of stopping the MAOI. Additive effects are expected if used in combination with other CNS stimulants including the beta-agonists. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Available data from published epidemiological studies and postmarketing case reports of pregnancy outcomes following inhaled albuterol use do not consistently demonstrate a risk of major birth defects or miscarriage. A peak fat burning Albuterol dose is normally that of 16 – 24mg per day. Administer using a calibrated measuring device. Codeine; Phenylephrine; Promethazine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. It is very important to not exceed the recommended dose of either the aerosol metered-dose or the nebulized solution formulations of albuterol. Coadministration with other drugs that prolong the QT interval may result in additive QT prolongation. An example of these types of Albuterol doses are as follows: Albuterol use at 24mg/day total (peak dose) Androgen deprivation therapy may prolong the QT/QTc interval. Monitor for altered therapeutic response to the beta-agonist. Dosage may be cautiously increased stepwise up to a maximum of 8 mg four times a … Beta-agonists and beta-blockers are pharmacologic opposites, and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. Additionally, increased albuterol use may indicate asthma destabilization. Formerly called metered dose inhalers (MDIs), HFAs give the drug through a small, handheld aerosol canister. Albuterol is preferred over other SABAs due to extensive safety-related information during pregnancy. This risk may be more clinically significant with long-acting beta-agonists (i.e., formoterol, arformoterol, indacaterol, olodaterol, salmeterol, umeclidinium; vilanterol) than with short-acting beta-agonists. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. In addition, there are postmarketing reports of torsade de pointes. QT prolongation and torsade de pointes (TdP) have been observed during haloperidol treatment. Betaxolol: (Moderate) Use of a beta-1-selective (cardioselective) beta blocker is recommended whenever possible when this combination of drugs must be used together. Hold the inhaler as directed for the inhaler type. Drugs with a possible risk for QT prolongation that should be used cautiously with vardenafil include the beta agonists. Doses were repeated every 2 hours until serum potassium concentrations fell to less than 5 mmol/L, the patient experienced adverse effects, or the maximum of 12 doses was reached. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists such as albuterol. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Tetrabenazine: (Minor) Tetrabenazine causes a small increase in the corrected QT interval (QTc). Study: Is Citrus Extract Sinensetin Anabolic? Metabolic acidosis has been reported with dichlorphenamide and albuterol aerosol and inhalation solution. Inhaled short-acting beta-2 agonists (SABAs) are the therapy of choice for preventing exercise-induced bronchospasm, and they are strongly recommended by the American Thoracic Society for EIB prophylaxis. albuterol metered dose inhaler dosage Best Quality and EXTRA LOW PRICES, inhaler dose metered albuterol dosage. I was given a perscription for an albuterol inhaler today. Nadolol: (Moderate) Use of a beta-1-selective (cardioselective) beta blocker is recommended whenever possible when this combination of drugs must be used together. At least one case of hypertension occurred in a patient with previous episodes of high blood pressure who was receiving albuterol and selegiline concurrently. Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. Buprenorphine; Naloxone: (Minor) Buprenorphine has been associated with QT prolongation and has a possible risk of torsade de pointes (TdP). This risk may be more clinically significant with long-acting beta-agonists than with short-acting beta-agonists. Mirtazapine: (Minor) There may be an increased risk for QT prolongation and torsade de pointes (TdP) during concurrent use of mirtazapine and short-acting beta-agonists. Quetiapine: (Minor) Limited data, including some case reports, suggest that quetiapine may be associated with a significant prolongation of the QTc interval in rare instances. Administered by Metered-Dose Inhaler and Spacer With Albuterol by Nebulizer in Adults Presenting to an Urban Emergency Department With Acute Asthma* Kenneth B. Newman, MD, FCCP; Scott Milne, MD; Cathy Hamilton, MPH; and Kent Hall, MD Study objectives: To determine the efficacy of albuterol by metered-dose inhaler (MDI) and spacer compared to a nebulizer. It should be recognized that paradoxical bronchospasm, when associated with inhaled formulations, frequently occurs with the first use of a new canister or vial. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Quinidine administration is associated with QT prolongation and torsades de pointes (TdP). Phentermine; Topiramate: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Even so, the Albuterol dosages required for the anabolic effects are the exact same doses required for the fat loss effects as well. However, large increases (greater than 60 msecs from pre-dose) have occurred in two patients receiving 6 mg doses. Inhalers using the new propellant may taste different and the spray of medication may not seem as strong. Females might exhibit greater sensitivity to Albuterol doses due to the fact that females generally tend to comprise a lower overall body mass and body weight. Additive side effects may occur between caffeine and beta-agonists. Use cautiously with promethazine, which has been reported to cause QT prolongation. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. FDA-approved labeling Max: 4 doses/day. Albuterol is a common medication in inhalers prescribed for people with asthma, chronic obstructive pulmonary disease (COPD), wheezing, or persistent cough after an upper respiratory infection. Asenapine: (Minor) Asenapine has been associated with QT prolongation. Additive side effects may occur between caffeine and beta-agonists. Ondansetron: (Minor) Ondansetron has been associated with QT prolongation and post-marketing reports of torsade de pointes (TdP). This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Monitor the patients lung and cardiovascular status closely. Doses should be delivered over 5 to 15 minutes. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. However, the cardiovascular effects of beta-2 agonists may be potentiated by concomitant use of MAOIs. Ezogabine has been associated with QT prolongation. BANs aerosolize albuterol solution but use an air compressor rather than a nebulizer. Beta-agonists and beta-blockers are pharmacologic opposites, and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. The action of albuterol inhalation powder should last for 4 to 6 hours. Acetaminophen; Butalbital; Caffeine; Codeine: (Moderate) Sensitive patients may wish to limit or avoid excessive caffeine intake from foods, beverages, dietary supplements and medications during therapy with beta-agonists. Albuterol is believed to work by activating adenylate cyclase, the enzyme responsible for generating cyclic AMP, an intracellular mediator. The Global Initiative for Asthma (GINA) guidelines recommend 2.5 mg via nebulization with face mask every 20 minutes for the first hour for acute exacerbations, with reassessment thereafter (further dosing not specified). Beta agonists infrequently produce cardiovascular adverse effects, mostly with high doses or in the setting of beta-agonist-induced hypokalemia. Not a Member? Beta-agonists and beta-blockers are pharmacologic opposites, and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. For acute asthma exacerbations, the NAEPP recommends 0.15 mg/kg/dose (Min: 2.5 mg/dose) vial oral inhalation every 20 minutes for 3 doses, then 0.15 to 0.3 mg/kg/dose (Max: 10 mg/dose) every 1 to 4 hours as needed or 0.5 mg/kg/hour by continuous nebulization. Weigh the risks of co-use, and where possible, allow a washout period after discontinuation of the MAOI before instituring beta-agonist treatment or vice-versa. Albuterol is used to prevent and treat difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness caused by lung diseases such as asthma and chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways). Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. Beta-agonists and beta-blockers are pharmacologic opposites, and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. Avoid administering saquinavir boosted with ritonavir with other drugs that may prolong the QT interval, such as beta-agonists. Articaine; Epinephrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Doses should be delivered over 5 to 15 minutes. We do not record any personal information entered above. Its effect on QTc interval is minimal (typically less than 5 msec), and the drug has been used safely in patients with cardiac disease (e.g., recent myocardial infarction, unstable angina, chronic heart failure). Weigh the risks of co-use, and where possible, allow a washout period after discontinuation of the MAOI before instituring beta-agonist treatment or vice-versa. Brompheniramine; Hydrocodone; Pseudoephedrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Inhaled short-acting beta-2 agonists (SABAs) are the therapy of choice for preventing exercise-induced bronchospasm, and they are strongly recommended by the American Thoracic Society for EIB prophylaxis. Drugs with a possible risk for QT prolongation and TdP that should be used cautiously with TCAs include the beta-agonists. Although QT interval prolongation has not been reported with gemtuzumab, it has been reported with other drugs that contain calicheamicin. Drugs with a possible risk for QT prolongation that should be used cautiously and with close monitoring with droperidol include beta-agonists. Doses should be delivered over 5 to 15 minutes. Beta-blockers will block the pulmonary effects of inhaled beta-agonists, and in some cases may exacerbate bronchospasm in patients with reactive airways. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Pharmacology, adverse reactions, warnings and side effects. QT prolongation has occurred with pasireotide at therapeutic and supra-therapeutic doses. Venlafaxine: (Minor) Venlafaxine administration is associated with a possible risk of QT prolongation; torsade de pointes (TdP) has been reported with post-marketing use. Fluphenazine: (Minor) Fluphenazine, a phenothiazine, is associated with a possible risk for QT prolongation. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Doxepin: (Minor) Tricyclic antidepressants (TCAs) share pharmacologic properties similar to the Class IA antiarrhythmic agents and may prolong the QT interval, particularly in overdose or with higher-dose prescription therapy (elevated serum concentrations). Loop diuretics: (Moderate) Loop diuretics may potentiate hypokalemia and ECG changes seen with beta agonists. Risperidone: (Minor) Use risperidone and short-acting beta-agonists together with caution due to the potential for additive QT prolongation and risk of torsade de pointes (TdP). Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. The likelihood of QT prolongation may increase with increasing concentrations of moxifloxacin, therefore the recommended dose or infusion rate should not be exceeded. The cardiovascular effects of beta-agonists may be potentiated by concomitant use of MAOIs. FDA-approved labeling recommends to not exceed 12 puffs/day. Drugs with a possible risk for QT prolongation and TdP that should be used cautiously with TCAs include the beta-agonists. Albuterol should be administered with extreme caution to patients being treated with monoamine oxidase inhibitor therapy (MAOI therapy) or within 2 weeks of discontinuation of such agents, because the action of albuterol on the vascular system may be potentiated. Chlorpheniramine; Dihydrocodeine; Phenylephrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. Beta-agonists have also been associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses and/or when associated with hypokalemia. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. Beta-agonists may cause adverse cardiovascular effects such as QT prolongation, usually at higher doses and/or when associated with hypokalemia. Use cautiously with promethazine, which has been reported to cause QT prolongation. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists such as albuterol, levalbuterol, metaproterenol, pirbuterol, and terbutaline. Pimozide: (Severe) Pimozide is associated with a well-established risk of QT prolongation and torsade de pointes (TdP) and should not be used with other drugs that might prolong the QT interval. Caffeine is a CNS-stimulant and beta-agonists are sympathomimetic agents. Naproxen; Pseudoephedrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Ribociclib: (Minor) Coadministration may result in additive effects on the QT interval. The first several days (normally spanning the first week or two) of use, the dose will be slowly ramped upwards until the final peak dose is achieved, after which the user will remain at the peak dose for the duration of use. Beta-agonists should be administered with extreme caution to patients being treated with drugs known to prolong the QT interval, such as vorinostat, because the action of beta-agonists on the cardiovascular system may be potentiated. Albuterol sulfate is a white to off-white crystalline solid. BACKGROUND: Historically, nebulizers have been preferred over metered-dose inhalers (MDIs) for the treatment of asthma exacerbations, although numerous studies have shown their equivalence. Doses should be delivered over 5 to 15 minutes. Monitor the patients lung and cardiovascular status closely. Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. This risk may be more clinically significant with long-acting beta-agonists versus short-acting beta-agonists. Phendimetrazine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Using more than the prescribed dose may be an indication of either a worsening of condition or improper administration. However, due to the lack of clinical data, mefloquine should be used with caution in patients receiving drugs that prolong the QT interval. Drugs with a possible risk for QT prolongation that should be used cautiously with mefloquine include the beta-agonists. PROVENTIL HFA Inhalation Aerosol is a pressurized metered-dose aerosol unit for oral inhalation. In general, the National Asthma Education and Prevention Program (NAEPP) Expert panel recommends albuterol 1.25 to 5 mg via oral inhalation every 4 to 8 hours as needed for bronchospasm. Glasdegib therapy may result in QT prolongation and ventricular arrhythmias including ventricular fibrillation and ventricular tachycardia. Give it for dry, hacking cough (especially nighttime cough), wheezing you can hear, or if your child is working harder to breathe. Case reports indicate that QT prolongation and torsade de pointes (TdP) can occur during donepezil therapy. QT prolongation and ventricular arrhythmias including fatal torsade de pointes have been reported with oxaliplatin use in postmarketing experience. Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Metronidazole: (Minor) Potential QT prolongation has been reported in limited case reports with metronidazole. Allow the mouthpiece to air-dry before next use (e.g., over-night). GINA recommends transfer to an acute care setting if there is no response to inhaled SABA within 1 to 2 hours or if more than 6 puffs are required during the first 2 hours; if more than 10 puffs are required in 3 to 4 hours, hospital admission is recommended. For acute asthma exacerbations, NAEPP recommends 0.15 mg/kg/dose (Min: 2.5 mg/dose) every 20 minutes for 3 doses, then 0.15 to 0.3 mg/kg/dose (Max: 10 mg/dose) every 1 to 4 hours as needed or 0.5 mg/kg/hour by continuous nebulization. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Aspirin, ASA; Caffeine; Dihydrocodeine: (Moderate) Sensitive patients may wish to limit or avoid excessive caffeine intake from foods, beverages, dietary supplements and medications during therapy with beta-agonists. However, the general manner of use of all stimulants for the purpose of fat loss is normally uniform in the following fashion: a peak dose is selected, which is the maximal daily dose that will be used during the cycle for fat loss. The elimination half-life of albuterol ranges from 2.7 to 6 hours, with orally administered albuterol having a shorter half-life than the inhaled product. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses and/or when associated with hypokalemia. In vitro studies have shown that dasatinib has the potential to prolong the QT interval. In general, inhaled long-acting beta-agonists are preferred since they are longer-acting and have fewer side effects than oral sustained-release agents. Beta-agonists and beta-blockers are pharmacologic opposites, and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. The optimal dosage for an acute COPD exacerbation is not established; adjust dose according to clinical symptoms and tolerance/adverse effects. Continue monitoring during concomitant treatment and increase the digoxin dose by 20 to 40% as necessary. The likelihood of QTc prolongation may increase with increasing dose of the drug; therefore, the recommended dose should not be exceeded especially in patients with renal or hepatic impairment where the Cmax and AUC are slightly higher. Diphenhydramine; Hydrocodone; Phenylephrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Beta-agonists and beta-blockers are pharmacologic opposites, and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. 1990;175(3):141-6. Clofazimine: (Minor) Monitor ECGs for QT prolongation when clofazimine is administered with short-acting beta-agonists. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval such as ribociclib. Crizotinib has been associated with concentration-dependent QT prolongation. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. Thyroid hormones may increase the risk of coronary insufficiency when sympathomimetic agents are administered to patients with coronary artery disease. Dopamine: (Major) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. Saquinavir: (Minor) Saquinavir boosted with ritonavir increases the QT interval in a dose-dependent fashion, which may increase the risk for serious arrhythmias such as torsades de pointes (TdP). The albuterol inhaler cost includes the device itself and the albuterol vial. A spacer (an attachment that increases the distance between the mouth and mouthpiece) is recommended as it ensures the medication goes deeper into the throat rather than being dispersed in the mouth. Beta-blockers will block the pulmonary effects of inhaled beta-agonists, and in some cases may exacerbate bronchospasm in patients with reactive airways. [31823] [43674] [44010] [49951] [59350] [64470] The National Asthma Education and Prevention Program (NAEPP) Asthma and Pregnancy Working Group include short-acting inhaled beta-2 agonists (SABAs) as first-line therapy for mild intermittent asthma during pregnancy, if treatment is required. Beta-agonists have also been associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses and/or when associated with hypokalemia. Avoid concurrent use of quinine with other drugs that may cause QT prolongation and TdP including beta-agonists. Methods: This was a randomized controlled double-blind multicenter study, conducted in emergency rooms (ER). Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with escitalopram. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Cases of long QT syndrome and torsade de pointes (TdP) have been described with maprotiline use, but rarely occur when the drug is used alone in normal prescribed doses and in the absence of other known risk factors for QT prolongation. In some patients, 1 puff every 4 hours may be sufficient. Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine: (Moderate) Sensitive patients may wish to limit or avoid excessive caffeine intake from foods, beverages, dietary supplements and medications during therapy with beta-agonists. If concomitant drug use is unavoidable, frequently monitor electrocardiograms. Although sympathomimetic agents are contraindicated for use with traditional non-selective monoamine oxidase inhibitors (MAOIs), hypertensive reactions generally are not expected to occur during concurrent use with rasagiline because of the selective monoamine oxidase-B (MAO-B) inhibition of rasagiline at manufacturer recommended doses. 2 to 4 mg PO every 6 to 8 hours. Androgen deprivation therapy may prolong the QT/QTc interval. Leuprolide; Norethindrone: (Minor) Consider whether the benefits of androgen deprivation therapy (i.e., leuprolide) outweigh the potential risks of QT prolongation in patients receiving short-acting beta-agonists. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. 6-15 minutes after it has been administered, it starts working to relieve and calm down the symptoms. The dose counter will count down each time the mouthpiece cap is opened and closed. This risk may be more clinically significant with long-acting beta-agonists as compared to short-acting beta-agonists. Carbonic anhydrase inhibitors: (Moderate) Albuterol may cause additive hypokalemia when coadministered with carbonic anhydrase inhibitors. Reduction or discontinuation of therapy, dose may be potentiated by concomitant use of MAOIs inhalation, albuterol can slowly! As to assess tolerance and determine the efficacy of albuterol would result QT. 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